In this study, the leaves of keladi tikus plant were extracted using methanol and then partitioned using nhexane, ethylacetate, and nbuthanol sequentially. Biological activity test of extract and fraction there of. This tropical plant found in damp, shady habitats and population of south east asian countries used it as alternative curative health supplement. The rhizomes of the plant have traditionally been used as an expectorant for coughs and as treatment for other pulmonary ailments. Introduction rodent tuber typhonium flagelliforme lodd.
Typhonium flagelliforme inhibits cancer cell growth in vitro. The raw material is somewhat toxic, being highly irritating to tissues that it contacts, and is mainly used externally. Typhonium flagelliforme keladi tikus is one such plant that is found locally in malaysia that has been studied for its inhibition of proliferation in human lung cancer cell line. Araceae commonly called rodent tuber was assessed towards different.
Typhonium flagelliforme inhibits the proliferation of. Typhonium flagelliforme rodent tuber is a herbal plant which grows up to 30cm in height. Hence, the antileukemia effect of typhonium flagelliforme was investigated in vitro and in vivo leukemic model. Typhonium flagelliforme araceae is a medicinal herb which is endowed with curative properties against a variety of illness including injuries, oedema, coughs, pulmonary ailments, bleeding and. Pdf typhonium flagelliforme is a prominent plant candidate from aroid family, endowing various curative properties against a variety of illness and. Rodent tuber grows wild in wasteland and is native to the south east asian countries. The objective of this study was to evaluate whether tf syrup tfs could decrease her2 neu and bcl2 expression as well as breast cancer volume bcv in mice. Micropropagation of rodent tuber typhonium flagelliforme lodd. Enhancement of the contents of anticancer bioactive. A cerebroside, with significant antihepatotoxic activity and phenylpropanoid glycosides isolated from flagelliforme typhyonium for the first time huang et al. Antibacterial and antioxidant activity of keladi tikus leaves extract typhonium flagelliforme lodd blume author links open overlay panelyunaharafarida. Abstractobjectiveto determine the inhibition activity of typhonium flagelliforme lodd.
Typhonium plus is a formula of selective herbs extract which in synergy strengthening works of typhonium flagelliforme. Uses, benefits, cures, side effects, nutrients in typhonium trilobatum. This page was last edited on 8 december 2019, at 15. Typhonium flagelliforme araceae is a medicinal herb which is endowed with curative properties against a variety of illness including injuries, oedema, coughs, pulmonary ailments, bleeding and cancer. Supervised classification karakter morfologi tanaman.
All structured data from the file and property namespaces is available under the creative commons cc0 license. Typhonium flagelliforme keladi tikus typhonium flagelliforme can be easily found in the indonesian forest. In vitro anticancer activity was assayed by mtt method on widr colon cancer cells. Typhonium flagelliforme keladi tikus is a herbal plant grows in east asia as traditional medicine to combat cancer. Researchers have reported its activity in lung cancer as a whole extract in. Typhonium trilobatum herb uses, benefits, cures, side. K ras is an oncogenic gtpase responsible for at least 1525% of all nonsmall cell lung cancer cases worldwide. An in vitro culture system was developed for typhonium flagelliforme using buds from the rhizomes. To download the pdf, click the download link below. Rodent tuber typhonium flagelliforme cut open to show presence of tiny insects inside. An typhonium flagelliforme in nahilalakip ha genus nga typhonium, ngan familia nga araceae.
Various extracts prepared from either the roots, tubers, stems or leaves were tested for cytotoxic activity on murine p388 leukaemia cells using the mtt assay method. It is being used traditionally in malaysia to treat cancer. Typhonium flagelliforme inhibits cancer cell growth in. In this study, the leaves of keladi tikus plant were extracted using. In vitro propagation of typhonium flagelliforme lodd. Ginklasipika han iucn an species komo diri gud kababarakan.
Typhonium flagelliforme in world checklist of selected plant families. Jurnal full paper teknologi article history cytotoxicity effects of typhonium flagelliforme received and clinacanthus nutans on. In vitro studies on continuous culture of continuous culture of human lymphoblasts cems showed that typhonium flagelliforme tf increases apoptosis. The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader if you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs alternatively, you can download the pdf file. Cell theory typhonium flagelliforme milieu externe. Lung cancer of both types is increasing with an alarming rate due to smoking habits in. This formula contains ribosome in acting protein rip, anti oxidant, and. Ayesha fatima department of pharmaceutical technology, faculty of. Keladi tikus rodent tuber typhonium flagelliforme lood bl. Bap is a cytokinintype pgr that is effective in inducing the production and propagation of buds from bud eyes gunawan, 1987.
Typhonium in world checklist of selected plant families. The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader. The board of trustees of the royal botanic gardens, kew. Antileukemic effects of typhonium flagelliforme on human. Typhonium flagelliforme international aroid society. Typhonium plus complementary alternative cancer treatment. Pdf typhonium flagelliforme decreases protein expression. In silico screening of mutated kras inhibitors from. The plant typhonium flagelliforme araceae, commonly known as the rodent tuber, is often included as an essential ingredient in various herbal remedies recommended for cancer. This page was last edited on 16 december 2019, at 17. Typhonium flagelliforme is currently being investigated for its cancer curing properties and has long been used as a traditional medicine in parts of asia.
Jan 01, 2001 read cytotoxic activity of typhonium flagelliforme araceae, phytotherapy research on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Typhonium flagelliforme or keladi tikus is a local. The plant list includes a further 14 scientific plant names of infraspecific rank for the genus typhonium. Alternatively, you can also download the pdf file directly to your computer, from where it can be opened using a pdf reader. These were murashige and skoog ms, nitsch and nitsch nn, gamborg b5 gb5 and white w of which ms medium was found to be the best medium for in vitro culture of t. Rodent tuber or typhonium flagelliforme extract and other herbs combination help in the detoxification of the blood system. All structured data from the file and property namespaces is available under the. Isolation and identification of chemical compounds in n. The genus typhonium suggested having about 50 species from india to polynesia and distributed 9 species in china 3. In vitro propagation of typhonium flagelliforme lodd blume. Nevertheless, it is a rarely seen plant in cultivation and. In silico screening of mutated kras inhibitors from malaysian typhonium flagelliforme for nonsmall cell lung cancer.
Typhonium flagelliforme, phytochemicals, traditional medicine. Analysis of preliminary phytochemical screening of typhonium. In order to evaluate its antiproliferative activity in vitro and to possibly identify the active chemical constituents, a bioactivity guided study was conducted on the extracts of this plant. Fraction from typhonium flagelliforme tuber citeseerx. Pdf the effects of different strength of ms media in. The plant typhonium flagelliforme, commonly known as rodent tuber in malaysia, is often used as a health supplement and traditional remedy. Typhonium flagelliforme, previously mistakenly referred as typhonium divaricatum nicolson and sivadasan, 1981, is commonly known as rodent tuber in malaysia. Typhonium flagelliforme inflorescence cut open to show.
Blume araceae is a malaysian plant used locally to combat cancer. Typhonium flagelliforme keladi tikus, from familia araceae, is widely used as an alternative therapy to treat various cancer. Supervised classification karakter morfologi tanaman keladi. The major aim of this study was to investigate the effect of. Typhonium flagelliforme is a species of flowering plant in the family araceae typhonium flagelliforme is native to guangdong, guangxi, yunnan, bangladesh, bhutan, cambodia, india, indonesia, laos. Lung cancer of both types is increasing with an alarming rate due to smoking habits in malaysia among men and women. Antibacterial and antioxidant activities of typhonium flagelliforme lodd. Dari beberapa penelitian disebutkan bahwa daun keladi tikus dimanfaatkan sebagai terapi alternatif pada kanker payudara, kolon, paruparu, serviks dan leukemia masood, dkk. Rodent tuber, keladi tikus, tu ban xia or lao shu yu botanical name. Typhonium trilobatum herb uses, benefits, cures, side effects. Natural products always offer alternate treatment therapies that are safe and effective. The plant list includes 115 scientific plant names of species rank for the genus typhonium. Blume diketahui memiliki aktivitas antikanker, detoksifikasi, antiinflamasi, antivirus dan antibakteri.
Typhonium flagelliforme is a prominent plant candidate from aroid family, endowing various curative properties against a variety of illness and infections. Pengaruh kombinasi ekstrak sirih merah piper crocatum. Cytotoxic activity of typhonium flagelliforme araceae. It has an oblong whitish tuber, triangular leaves ad a spathe. Flower color is purplelavender and blooms in summer. The plant typhonium flagelliforme, commonly known as rodent tuber in malaysia, is often used as a health supplement and traditional remedy for alternative cancer therapies, including leukemia. Images and links for typhonium flagelliforme from the international aroid society. Typhonium flagelliforme extract and other herbs combine help in the detoxification of the blood system.
In vitro ultramorphological assessment of apoptosis on cemss. List of various diseases cured by typhonium trilobatum. The plant list includes a further 14 scientific plant names of. Its active ingredients including phytol and its derivative, hexadecanoic acid, 1hexadecene, and pheophorbide related compoundshave shown some promising results as. Nov 21, 2017 rodent tuber typhonium flagelliforme cut open to show presence of tiny insects inside. Oct 30, 2018 typhonium flagelliforme in world checklist of selected plant families. Typhonium flagelliforme tf is a tropical plant, traditionally used by the ethnic population of malaysia for the cure of various cancers. Hence, the antileukemia effect of typhonium flagelliforme was investigated in. Rodent tuber has a broad array of bioactive compounds with anticancer activity against lung, breast2, liver3, blood4. The situation for chinese herbalists is complicated by the fact that the report of ephedrine in pinellia has been from tests with the source material pinellia ternata referred to as northern banxia, pictured upper left while most of the pinellia used in china and in the west is actually from a related plant that has the same uses. A phylogeny of the areae araceae implies that typhonium, sauromatum, and the australian species of typhonium are distinct clades.
The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader if you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs. This plant had shown to induce antiproliferative effect as well as apoptosis in cancer cells. Even one variety of typhonium, typhonium flagelliforme, is used as banxia in china. Detection of gammairradiated mutant of rodent tuber. To date, there has been no literature reported on the mechanism of typhonium flagelliforme and its effects on leukemia.
The plant typhonium flagelliforme araceae, commonly known as the rodent tuber, is often included as an essential ingredient in various herbal remedies recommended for cancer therapies in malaysia. Pdf antibacterial and antioxidant activities of typhonium. Female flowers 1loculed with 1 or 2or 3 orthotropous basal ovules. The situation for chinese herbalists is complicated by the fact that the report of ephedrine in pinellia has been from tests with the source material pinellia ternata referred to as northern banxia, pictured. It has been used for treating internal injuries and edema. Investigations of antioxidant and antibacterial activities. How typhonium trilobatum is effective for various diseases is listed in. S2, wahono s3 1faculty of pharmacy, pancasila university, jakarta 12640, indonesia 2department of chemistry, fmipa, university of indonesia, depok 1624, indonesia 3agency for the assessment and apllication of technology, indonesia bppt. In vitro ultramorphological assessment of apoptosis on.
Antiproliferation activity of tuber protein from typhonium flagelliforme lodd. Pinellia refers to the tuber of pinellia ternata see figure 1, known to the chinese as banxia. Nevertheless, it is a rarely seen plant in cultivation and not often seen in collections. The antioxidant and antibacterial activity of different extracts from of typhonium flagelliforme l. Names of typhonium trilobatum in various languages of the world are also given. Files are available under licenses specified on their description page. Pages in category typhonium the following 4 pages are in this category, out of 4 total. Introduction typhonium flagelliforme is a medicinal herb which belongs to the araceae arum family.
Typhonium flagelliforme is a species of flowering plant in the family araceae typhonium flagelliforme is native to guangdong, guangxi, yunnan, bangladesh, bhutan. Typhonium flagelliforme from the family araceae is locally known as rodent tuber. Compounds in mutant clones of rodent tuber typhonium flagelliforme lodd. Typhonium flagelliforme inhibits the proliferation of murine. This plant had shown to induce antiproliferative effect as well as. Typhonium flagelliforme patterned leaf form aga190001 aug. To determine the effects of different strength of murashige and skoog ms media full. S2, wahono s3 1faculty of pharmacy, pancasila university, jakarta 12640, indonesia. How typhonium trilobatum is effective for various diseases is listed in repertory format.
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